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ProAnalyst 1.02 MS-DOS
PROANALYST is an easy-to-use MS-DOS application to assist in the analysis of multiple protein alignments, studying the structure-function and structure-activity relationships in protein/peptide families.
Download  (542 kb, 30-Aug-1996)

ProMSED2 Windows
ProMSED2 (Protein Multiple Sequence EDitor-2), Windows application for both automatic and manual DNA and protein sequence alignment, editing, comparison and analysis.
Web Site Home Web Site: BioInformer Download  (461 kb, 06-Feb-1997)

ProbeQuest Assistant Windows
ProbeQuest Assistant creates the following files for a probe/primer design: (1) List of exon-exon junction sites. (2) List of specified regions such as CDS. (3) List of restriction enzyme recognition sites. (4) Sequence file of genomes. (5) Sequence file of RNA regions in genome. (6) Multiple alignment file with position data.
Web Site Home Web Site: DYNACOM Co., Ltd.

ProfileWeight and ProPlot Unix
This package consists of two programs PROFILEWEIGHT and PROPLOT. PROFILEWEIGHT is a program to produce an alignment profile for use by the GCG program package. PROPLOT is a program for displaying dot-plots of (i) sequence versus sequence, (ii) sequence versus profile, and (iii) profile versus profile.
Download  (200 kb, 20-Sep-1993)

Protein Science Data Files MS-DOS  Mac  Unix  VMS
Data files for evaluating sequence comparison programs as used in the paper, "Comparison of methods for searching protein sequence databases" (1995) Prot. Sci. 4:1145-1160.
Download  (65 kb, 24-Dec-1995)

RNA Baser - rRNA sequence assembly and analysis Mac  Windows
RNA Baser represents an extension of DNA Baser, specialized in processing rRNA sequences. It is optimized for early integration of sequence and metadata. This way, the metadata will stay attached to the primary sequence information throughout the complete workflow of sequence analysis, until final submission. * * * * * * * * * * * * * * * * * * * * * * * RNA Baser it is optimized for data exchange with standard non-commercial software used for rRNA sequence analysis and submission. This is a joint project of HeracleSoftware, Ribocon GmbH and Max Planck Institute for Marine Microbiology in Bremen, Germany
Web Site Home Web Site: RNA Baser - sequence assembly and analysis

Redasoft Internet Browser  Windows
Redasoft offers exciting new software tools designed to help you create and publish high quality genetic maps and perform sequence analysis quickly and easily.
Web Site Home Web Site: Redasoft

Restriction Map Alignment Unix
This program reads restriction maps and deciphers alignments using a quantic map alignment algorithm.
Web Site Home Web Site: USC Computational Biology

SAGA 0.9 Unix
Sequence Alignment by Genetic Algorithm. SAGA is a multiple alignment program using a GA to minimise the Objective Functionnown as Weighted Sums of Pairs with affine or semi affine gap penalties.
Download  (1514 kb, 27-Apr-1996)

SAM-T99 Internet Browser  Linux  Unix
SAM-T99 is a perl script using the SAM suite of tools for hidden Markov models to search for and align homologs of protein sequences. The web site uses the resulting alignment to do protein structure prediction(both fold recognition and secondary-structure prediction).
Web Site Home Web Site: HMM-based sequence query, Target99

SAM: Sequence Alignment and Modeling System Linux  Unix
A hidden Markov modeling suite software system.Version 3.0 now includes the SAM-T99 script forfinding and aligning remote homologs of proteins.(Free to academics and non-profits)
Web Site Home Web Site: Baskin School of Engineering, UC Santa Cruz

SC rate Unix
A Perl5 program that evaluates the accuracy of protein sequence alignment with very low sequence identity.
Web Site Home Web Site: Medical Research Council

SEQAID 3.81 MS-DOS
DNA and protein sequence analysis package.
Download  (215 kb, 01-Aug-1991)

SEQtools Windows
Program package for handling and analysis of nucleotide and protein sequences. In addition to many trivial functions, SEQtools includes advanced facilities for automated blast searching, sequence retrieval and design and layout of microarrays.
Web Site Home Web Site: SEQtools

SIM Internet Browser
Finds a user-defined number of best non-intersecting alignments between two protein sequences. Pairwise alignments can be viewed graphically.
Web Site Home Web Site: Expasy

SIM (MS-DOS) MS-DOS
The SIM program finds 'k' best non-intersecting alignments between two sequences or within one sequence. Using dynamic programming techniques, SIM is guaranteed to find optimal alignments.
Download  (20 kb, 12-Feb-1991)

SIM (Unix) Unix
The SIM program finds 'k' best non-intersecting alignments between two sequences or within one sequence. Using dynamic programming techniques, SIM is guaranteed to find optimal alignments.
Download  (17 kb, 05-May-1992)

SSS align Unix
A software implementation of the Smith/Waterman best local similarity algorithm which, in addition to the traditional Dayhoff PAM scoring scheme, has the ability to use secondary structure prediction in order to align sequences which have identities as low as 15% and still identify those sequences as significant.
Web Site Home Web Site: University of Edinburgh

STAMP Unix
A suite of programs for the comparison and alignment of protein three dimensional structures. The suite will multiply align structures and produce a corresponding sequence alignment with confidence values associated with each aligned position.
Web Site Home Web Site: The Barton Group

STRAP Internet Browser  Linux  Mac  Unix  Windows
The free computer program STRAP aligns proteins by sequence and 3D-structure. It supports the simultaneous analysis of hundreds of proteins and integrates amino acid sequence, secondary structure, 3D-structure and genomic- and mRNA-sequence and residue annotation. Protein files can easily loaded with Drag-and-Drop. The computed alignments can be exported as MS-Word, PDF, PS and raw text. Sequence features like glycosylated ore phosphorylated amino acids and active site residues are highlighted on the sequence. STRAP takes advantage of the 3D-viewer Pymol which is tightly integrated. Currently 80 Bioinformatics algorithms from authors from all over the world are embedded. These include structure prediction, sequence alignment, 3D-superposition, 3D-visualization, Blast and phylogenetic analysis.
Web Site Home Web Site: STRAP - A workbench for Protein Sequences and Structures

ScanPS (Unix) Unix
A local alignment method to search protein sequence databases with a query sequence or multiple alignment, and also allows all pairwise comparisons to be made between a set of sequences and can estimate the statistical significance of the alignments.
Web Site Home Web Site: The Barton Group

SeaView Unix
This is a multiple sequence alignment editor.
Web Site Home Web Site: Laboratoire de biometrie, genetique et biologie des populations

SeqAlign Unix  VMS
SEQALIGN is a demonstration program which uses a modified Myers and Miller algorithm. The program introduces position-specific gap penalties into the existing algorithm. Thus, residue-dependent information such as structural preferences and existing gaps in the sequences can be applied to the alignment program.
Download  (65 kb, 17-Sep-1994)

SeqLogo Mac
Displaying consensus sequences by means of 'logos'.
Download  (500 kb, 04-Feb-1991)

SeqPup Mac  Windows
A biosequence sequence editor and analysis program for multiple sequence alignments and single sequence editing.
Web Site Home Web Site: Indiana University

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